Potential Health Hazards from Sodium Bicarbonate While sodium bicarbonate is generally not considered to be amongst the most harmful of chemicals, exposure to large amounts may result in some adverse health effects, such as: Coughing and sneezing if a … Flush eyes with plenty of water and seek medical attention if irritation occurs. Chronic ingestion of bicarbonate may rarely cause intravascular volume expansion with resultant hyporeninemia and hypoaldosteronemia. Acta Chir Scand Suppl 530 (1986): 97-9, 23. These side effects may go away during treatment as your body adjusts to the medicine. Rare cases of sodium bicarbonate abuse have been associated with features of Munchausen syndrome. Ann Intern Med 112 (1990): 492-8. Toll free: 1.800.807.0783, Canada Inhalation Move to fresh air. J Clin Psychiatry 49 (1988): 168, 3. Sodium bicarbonate is a white solid that is crystalline, but often appears as a fine powder. It is broadly used as an physiological buffer in in vitro applications. In this rare circumstance, the serum potassium may be elevated. Rapid infusion of hyperosmolar sodium bicarbonate has been associated with intraventricular hemorrhage in the pediatric literature. Individual should be removed from exposure and immediately moved to an area with fresh air. PRODUCT AND COMPANY IDENTIFICATION 1.1 Product identifiers Product name : Sodium bicarbonate Product Number : S5761 Brand : Sigma REACH No. 77, No. These effects have been associated with rapid or prolonged administration. Irritability and tetany have been associated with sodium bicarbonate-induced alkalosis or hypernatremia. Rare cases of sodium bicarbonate abuse have been associated with features of Munchausen syndrome. Major Potential Hazard, High plausibility. Gastroenterology 87 (1984): 1014-21, 20. Page 5 of 5 MSDS - SODIUM BICARBONATE 16. Material Safety Data Sheet Sodium bicarbonate MSDS Section 1: Chemical Product and Company Identification Product Name: Sodium bicarbonate Catalog Codes: SLS3241, SLS2446, SLS3868 CAS#: 144-55-8 RTECS: VZ0950000 TSCA: TSCA 8(b) inventory: Sodium bicarbonate CI#: Not available. Over-the-counter antacid products containing sodium bicarbonate … Eyes 1161 Oak Valley Dr. Sodium bicarbonate (IUPAC name: sodium hydrogen carbonate), commonly known as baking soda or bicarbonate of soda, is a chemical compound with the formula NaHCO3. Toll free: 1.888.362.2007, VelocityEHS | Humantech If this chemical gets into a worker’s eyes, it can cause mild to moderate irritation. A slow rate of administration of a properly diluted solution into a large bore needle and vein is recommended if IV administration is necessary. Eye contact can cause permanent corneal injury and possible burns. Mastrangelo MR, Moore EW "Spontaneous rupture of the stomach in a healthy adult man after sodium bicarbonate ingestion." It has a slightly salty, alkaline taste resembling that of washing soda (sodium carbonate). Protective gloves and clothing should be worn. Carbon dioxide is an asphyxiant, and soda ash is an irritant. The main side effect from medicinal use is weight gain from its sodium content. The sodium bicarbonate is decomposed by heat producing sodium carbonate. [Ref], 1. View information & documentation regarding Sodium bicarbonate, including CAS, MSDS & more. Synonym: Baking Soda; Bicarbonate of soda; Sodium The mortality associated with gastric rupture is as high as 65%. Papile LA, Burstein J, Burstein R, Koffler H, Koops B "Relationship of intravenous sodium bicarbonate infusions and cerebral intraventricular hemorrhage." Am J Emerg Med 12 (1994): 57-9, 9. [Ref], Cardiovascular side effects have included decreased cardiac contractility possibly resulting from infusion of sodium bicarbonate in patients with severe acidosis. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of carbon monoxide, carbon dioxide and sodium oxides. If improperly handled, or in the event of accidental exposure, sodium carbonate can pose several hazards to your health and safety. [Ref], Urinary alkalinization from bicarbonate can cause a falsely positive colorimetric assay for protein. Prakash P, Saxena S "Complication of sodium bicarbonate therapy--a case report." Sodium bicarbonate is the active ingredient in baking soda. How to use Sodium Bicarbonate Take this medication by mouth , usually every 4 hours as needed or as directed by your doctor. Other Information Disclaimer: The information and recommendations contained herein are, to th e best of Pon Pure Chemicals Group knowledge and belief, accurate and reliable as of the date issue d. You can contact Pon Pure Chemicals Group to ensure that this document is the most current Sodium bicarbonate is a common ingredient in cleaning, detergent and degreasing products. (NTP, 1992) May be harmful if swallowed (H303). cas:25155-30-0 msds dodecyl benzenesulfonic acid, sodium salt cas:1396762-34-7 msds SodiuM 3-chloro-2,4-difluorobenzoate cas:873950-18-6 msds Atorvastatin Cyclic (Fluorophenyl) Impurity Sodium bicarbonate should be stored in a tightly closed container and placed in a cool, dry, well-ventilated area. Indian J Pediatr 45 (1978): 277-8, 16. Cooper DJ, Worthley LI "Adverse haemodynamic effects of sodium bicarbonate in metabolic acidosis." [Ref], The respiratory drive may be suppressed after bicarbonate administration due to increased venous C02 concentration. Acta Neurol Scand 57 (1978): 239-47, 13. Medically reviewed by Drugs.com. Nephrol Dialysis Transplant 14 (1999): 452-4, 11. Product should be treated as a chemical and is not for consumption as it has been stored with other nonfood-grade chemicals. Conditions to Avoid Incompatible products. of baking soda diluted in one glass of water every two hours. Keep away from acids, excessive heat and moisture. Intensive Care Med 13 (1987): 425-7, 17. 8. Potential Health Hazards from Sodium Bicarbonate. Excess heat. Arch Intern Med 136 (1976): 1179-80, 10. It works by quickly neutralizing stomach acid and temporarily relieving symptoms of acid reflux. Sodium bicarbonate is broadly used as a physiological buffer in cell culture applications. Incompatible Materials Strong oxidizing agents, Metals, Strong acids Hazardous Decomposition ProductsHydrogen chloride gas, Sodium oxides Suite 1750 Get medical attention immediately if symptoms occur. J Pediatr 93 (1978): 834-6, 14. Last updated on Feb 19, 2020. Unlimited SDS Searches, 5 FREE Downloads, No Credit Card, The National Institute for Occupational Safety and Health (NIOSH), COVID-19 Workplace Standards Update: State OSHA Agencies Continue Development of Regulations to Protect Workers, OSHA Is Issuing Large Fines to Companies for COVID-19 Related Violations, VelocityEHS Offers HazCom & Chemical Safety Support for Emergency Responders, Businesses and Others Affected by Hurricane Delta, Coughing and sneezing if a high concentration of dust has been inhaled, Gastrointestinal irritation can occur if large amounts have been ingested, Mild irritation, such as redness and slight pain, may result from eye contact, In dry form, it’s typically non-irritating to intact skin; however, it can cause irritation to damaged skin when moisture is present. Most Important Symptoms and Effects Both Acute and Delayed Thermal decomposition products are carbon dioxide and sodium carbonate (soda ash). First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. All rights reserved. Wu DJ, Mifune J, Taga K, Hifumi S, Takahashi Y, Yamashida S, Nishioka S, Murakami T, Tanaka T "Anginal attack following a sodium bicarbonate and hydrocortisone injection." Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Sodium bicarbonate Revision Date 18-Jan-2018 4. These patients often present with an otherwise unexplained hypokalemic hypochloremic metabolic alkalosis. 77, No. However, if you vomit or go into convulsions, do not drink anything, to keep the air passages clear and patent. Oakville, ON L6J 3J3 J Crit Illn 8 (1993): 224-46, 6. Cooper DJ, Walley KR, Wiggs BR, Russell JA "Bicarbonate does not improve hemodynamics in critically ill patients who have lactic acidosisis." Sodium Carbonate, Anhydrous (497-19-8) Listed on the United States TSCA (Toxic Substances Control Act) inventory SARA Section 311/312 Hazard Classes Health hazard - Skin corrosion or Irritation Health hazard - Serious eye damage or eye irritation 3) Inhalation Sodium Bicarbonate Powder 10. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Along with its needed effects, sodium bicarbonate may cause some unwanted effects. Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. Jpn Heart J 31 (1990): 109-13, 4. Inhalation of this chemical can lead to adverse effects such as respiratory tract irritation, coughing, shortness of breath, and pulmonary edema. EH&S Blog Health & Safety Safety with Sodium Bicarbonate, 222 Merchandise Mart Plaza That dose is for individuals older than 12 years of age. Hazard PB, Griffin JP "Sodium bicarbonate in the management of systemic acidosis." The natural mineral form is nahcolite. Get medical attention. Arieff AI "Managing metabolic acidosis: update on the sodium bicarbonate controversy." Lou HC, Lassen NA, Fris-Hansen B "Decreased cerebral blood flow after administration of sodium bicarbonate in the distressed newborn infant." Sodium Bicarbonate (sodium bicarbonate)." Check with your doctor as soon as possible if any of the following side effects occur while taking sodium bicarbonate: Some side effects of sodium bicarbonate may occur that usually do not need medical attention. Sodium bicarbonate, according to the National Institutes of Health Toxicology Data Network, has a low toxic risk. Seek medical attention if a large amount is swallowed. Chicago, IL 60654 SAFETY DATA SHEET. [Ref], As an antacid, sodium bicarbonate, especially after excess food or liquid, can cause excess gas release (when combined with gastric acid). ARM & HAMMER™ Sodium Bicarbonate - Grade 1 TFF Safety Data Sheet According To Federal Register / Vol. Heartburn Relief. Griffith J, White P "Acute asthma precipitated by accidental inhalation of sodium bicarbonate granules (Carbex)." SAFETY DATA SHEET Version 4.6 Revision Date 02/26/2014 Print Date 03/20/2014 1. omeprazole, famotidine, allopurinol, ranitidine, Zantac, Prilosec, calcium carbonate, epinephrine, Humalog, sodium bicarbonate. VelocityEHS®, MSDSonline® and Humantech® are proprietary trademarks of VelocityEHS. Scott Med J 34 (1989): 534-5. You may report them to the FDA. [Ref], Gastrointestinal side effects associated with oral administration have rarely included gastric rupture. Applies to sodium bicarbonate: granule, solution, tablet. Toll free: 1.866.919.7922. 7. © Copyright 2019 VelocityEHS. Some side effects may not be reported. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Side Effects & Safety When taken by mouth: Sodium bicarbonate is LIKELY SAFE when taken appropriately, short-term. Available for Android and iOS devices. Okada H, Inoue T, Takahira S, Sugahara S, Nakamoto H, Suzuki H "Daytime hypertension, sleep apnea and metabolic alkalosis in a haemodialysis patient - the result of sodium bicarbonate abuse." Cutis 32 (1983): 65-6, 15. OSHA Vacated PELs: Sodium bicarbonate: No OSHA Vacated PELs are listed for this chemical. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Sodium Bicarbonate Safety Data Sheet according to Federal Register / Vol. 02/02/2017 Date of Issue: 02/02/2017 Version: 2.0 SECTION 1: 02/02/2017 EN (English US) 1/6 IDENTIFICATION While sodium bicarbonate is generally not considered to be amongst the most harmful of chemicals, exposure to large amounts may result in some adverse health effects, such as: Safety Precautions When Handling Sodium Bicarbonate. Lazebnik N, Iellin A, Michowitz M "Spontaneous rupture of the normal stomach after sodium bicarbonate ingestion." Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations … The pKa for bicarbonate <-> carbonic acid reaction is 6.4 The pKa for bicarbonate <-> carbonate reaction is 10.3. T2E 6J7 1.866.620.6034 Safety Data Sheet Sodium Bicarbonate Document No. Bleske BE, Warren EW, Rice TL, Gilligan LJ, Tait AR "Effect of high-dose sodium bicarbonate on the vasopressor effects of epinephrine during cardiopulmonary resuscitation." Chronic ingestion of bicarbonate may rarely cause intravascular volume expansion with resultant hyporeninemia and hypoaldosteronemia. Do NOT induce vomiting. [Ref], Local side effects have included IV site pain, venous irritation, and extravasation. Clin Radiol 49 (1994): 435, 12. M-D6-010 [Ref], Renal side effects have rarely included "False proteinuria". Skin 3 Effective date : 01.06.2015 Page 2 of 6 Sodium Bicarbonate, Reagent Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com CAS 144-55-8 Sodium Bicarbonate 100 % Percentages are by weight SECTION 4 : First aid measures Description of first aid measures Sodium Bicarbonate Safety Data Sheet According To Federal Register / Vol. Kennedy S "Sodium bicarbonate abuse in anorexia nervosa." Although the following side effects occur very rarely when this medicine is taken as recommended, they may be more likely to occur if it is taken: in large doses, for a long time, or by patients with kidney disease. If sodium bicarbonate dust in the worker’s breathing zone can’t be controlled with ventilation or other engineering means, workers should wear respirators or dust masks approved by a certification organization, such as The National Institute for Occupational Safety and Health (NIOSH), for protection against this chemical. Wash skin with plenty of soap and water and seek medical attention if irritation occurs. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. One of the hazards of taking sodium hydrogen carbonate or sodium bicarbonate is overdose 1. [Ref], Experimentally, the administration of intravenous hypertonic sodium bicarbonate has been associated with increased serum osmolality, decreased ionized serum calcium (which is associated with decreased myocardial contractility), and peripheral vasodilation. It’s odorless, non-combustible and reacts with acids to release carbon dioxide gas and heat. [Ref], Respiratory side effects have included suppressed respiratory drive. Material Safety Data Sheet Sodium carbonate ACC# 21080 Section 1 - Chemical Product and Company Identification MSDS Name: Sodium carbonate Catalog Numbers: AC123670000, AC123670010, AC123670025, AC206800000, AC206800010, AC206800025, Pharmacotherapy 15 (1995): 660-4, 19. South Med J 73 (1980): 1339-42,1348, 2. In this rare circumstance, the serum potassium may be elevated. J Crit Care 9 (1994): 255-61, 18. If the chemical has been contaminated, contact your state’s Environmental Protection Agency for disposal procedures specific to your area. Without adequate ventilation, worsened systemic acidosis could develop. It's a slight skin and eye irritant, and can cause increased thirst. 77, No. Sodium bicarbonate has many applications in the workplace as well, including being used in fire extinguishers or in an agricultural setting as a way to combat the growth of fungus on farms. Sodium bicarbonate also is an active ingredient in antacid products used to relieve heartburn and treat acid indigestion. Side effects have rarely included intravascular volume expansion with resultant hyporeninemia and hypoaldosteronemia.[Ref]. Br J Psychiatry 149 (1986): 502-3, 5. Ann Arbor, MI 48108 Drink plenty of water and seek medical attention if discomfort persists. Oster JR, Perez GO, Rosen MS "Hyporeninemic hypoaldosteronism after chronic sodium bicarbonate abuse." Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to sodium bicarbonate: compounding powder, intravenous solution, oral tablet, Metabolic side effects have included metabolic alkalosis, hypernatremia/hyperosmolarity, hypochloremia, and hypokalemia. Hypernatremia may cause water retention, weight gain, and edema, which may be important in some patients with congestive heart failure, renal insufficiency, or severe liver disease. International Transportation: Sodium Bicarbonate has no U.N. number, and is not regulated under international rail, highway, water, or air transport regulations. This site requires Javascript to be enabled for full functionality. It is a component of the mineral natronand is f… 58 / Monday, March 26, 2012 / Rules And Regulations And According To The Hazardous Products Regulation (February 11, 2015). Application Thomas SH, Stone CK "Acute toxicity from baking soda ingestion." Vacuuming or wet sweeping are recommended to avoid dispersing dust. Rao RS, Graver ML, Urivetsky M, Scharf SM "Mechanisms of myocardial depression after bolus injection of sodium bicarbonate." SODIUM BICARBONATE . Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Some experts recommend invasive hemodynamic monitoring in acidotic patients before the administration of bicarbonate. Sodium bicarbonate systemic 5 grain (325 mg) (CL 205), We comply with the HONcode standard for trustworthy health information -, Sodium bicarbonate Oral, Intravenous, Subcutaneous. Take sodium bicarbonate as your doctor’s prescription instructs 2 3.The general recommendation for heartburn is 1/2 tsp. Ann Intern Med 101 (1984): 649-50, 22. Since sodium bicarbonate is most-often seen in a powder-like state, chemical safety goggles should be worn and an area to wash eyes and skin should be located in the work area. The traditional Solvay process is utilized in most parts of the world, with the exception of the U.S., where all production is based on the minerals which contain sodium carbonate. Brismar B, Strandberg A, Wiklund B "Stomach rupture following ingestion of sodium bicarbonate." Fordtran JS, Morawski SG, Santa Ana CA, Rector FC, Jr "Gas production after reaction of sodium bicarbonate and hydrochloric acid." • DNELAcute        â€  sodium bicarbonate is considered to be of no toxicological concern, in acute studies no local irritation was noted. In the event exposure occurs, the following steps should be taken: 1) Eye Contact 58 / Monday, March 26, 2012 / Rules and Regulations 09/13/2019 EN (English US) 5/6 Sodium Bicarbonate (144-55-8) LC50 fish 1 8250 - 9000 mg/l EC50 Daphnia 1 2350 mg/l 58 / Monday, March 26, 2012 / Rules And Regulations 03/12/2015 EN (English US) 2/5 Ingestion: Rinse mouth. For more information on sodium bicarbonate and other chemicals, browse our extensive database of MSDS information. [Ref], Nervous system side effects have included irritability, tetany, mental stupor, coma, and intraventricular hemorrhage.[Ref]. Sodium bicarbonate (better known to the world as baking soda) is a soluble white powder that is crystalline but often appears as a fine powder. 586 Argus Road Linford SM, James HD "Sodium bicarbonate abuse: a case report." J Clin Gastroenterol 8 (1986): 454-6, 21. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. "Product Information. Exposure to moist air or water. Seek medical attention immediately if any breathing difficulty occurs. Sodium bicarbonate serves a variety of purposes, ranging from household uses such as baking and cleaning, to treating minor medical ailments like sunburn and insect bites. Alkalinizing agents (Includes potassium bicarbonate/sodium bicarbonate) ↔ sodium/water balance. Sodum bicarbonate has two pKas, 6.4 and 10.3. Even though sodium bicarbonate is relatively safe compared to other chemicals in the workplace, as with any chemical, all unnecessary exposure should be avoided. Suite 300 Sodium hydrogen carbonate CAS 144-55-8 for analysis EMSURE® ACS,Reag.Ph Eur - Find MSDS or SDS, a COA, data sheets and more information. Downs NM, Stonebridge PA "Gastric rupture due to excessive sodium bicarbonate ingestion." 2) Skin Contact Managing Exposure to Sodium Bicarbonate Page 1 of 4 Chief Medical Supplies Ltd. 411 – 19 Street, S. E. Calgary, AB., Canada. If sodium bicarbonate spills, it can be recovered and re-used if contamination hasn’t occurred. Applies to: Congestive Heart … Avoid dust formation. Cellulitis, tissue necrosis, ulceration, or skin sloughing have possibly been the result of extravasation. Stability and Reactivity Reactivity: N/A Chemical Stability: Stable Conditions of Stability/Instability: N/A Stabilizers needed: None Safety issue indicated by appearance change: N/A Other: N/A Hazardous Reactions: N/A Hazardous Polymerization: Does not occur Conditions to avoid: N/A Classes of Incompatible Materials: Oxidizers, Strong Acids, Strong Bases. Speer ME, Rudolph AJ "Calcification of superficial scalp veins secondary to intravenous infusion of sodium bicarbonate and calcium chloride." Astra USA, Westborough, MA. 4) Ingestion It is a salt composed of a sodium cation (Na ) and a bicarbonate anion (HCO3 ). Sigma-Aldrich offers a number of Sodium bicarbonate products. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. SODIUM BICARBONATE Safety Data Sheet Page 3 of 3 Section 14: Transport Information U.S. Department of Transportation (DOT) Identification Number: Sodium Bicarbonate is not a DOT Hazardous Material. P 103 / USA Issuing date 12/09/2008 / Report version 1.0 Copyright 2008, SOLVAY CHEMICALS, INC. All Rights Reserved Due to greater permeability of the blood-brain barrier to hydrogen than to bicarbonate, the pH of cerebrospinal fluid may significantly decrease during sodium bicarbonate administration, which can cause mental stupor or coma. Hazard class: Acute toxicity, oral (Category 5). Cleaning Products & Solvents. Sodium chloride Revision Date 17-Apr-2019 Reactive Hazard None known, based on information available Stability Hygroscopic. Links with this icon indicate that you are leaving the CDC website.. Resembling that of washing soda ( sodium carbonate ). lou HC, Na... As high as 65 % Javascript to be enabled for full functionality:. 1995 ): 1179-80, 10 respiratory tract irritation, coughing, shortness of breath, and cause. 502-3, 5: 649-50, 22 acta Neurol Scand 57 ( )! 12 years of age dioxide is an asphyxiant, and pulmonary edema of No toxicological concern, in Acute No... State’Sâ Environmental Protection Agency for disposal procedures specific to your area an physiological buffer in! Injury and possible burns 's a slight skin and eye irritant, and soda ash ). hazards... If IV administration is necessary bicarbonate: granule, solution, tablet to effects! Have been associated with features of Munchausen syndrome, Renal side effects have included respiratory. To tell you about ways to prevent or reduce some of these side effects been! Register / Vol from bicarbonate can cause mild to moderate irritation IDENTIFICATION 1.1 Product identifiers Product name: bicarbonate... One glass of water for at least 15 minutes with plenty of water for at least minutes! For at least 15 minutes often appears as a physiological buffer in in vitro applications Managing acidosis! Bicarbonate Product Number: S5761 Brand: Sigma REACH No with acids to release carbon dioxide an... Stonebridge PA `` gastric rupture the chemical has been contaminated, Contact state’sÂ... Your body adjusts to the medicine educational purposes only and is not for consumption as it has been with. Placed in a healthy adult man after sodium bicarbonate is a common ingredient in cleaning, detergent and degreasing...., Gastrointestinal side effects have rarely included intravascular volume expansion with resultant hyporeninemia and hypoaldosteronemia [. Medication by mouth: sodium bicarbonate is considered to be of No toxicological concern, Acute! Medicinal use is weight gain from its sodium content acidosis. about ways to prevent or reduce some these... And water and seek medical attention if irritation occurs effects associated with features of Munchausen syndrome systemic.... After bolus injection of sodium bicarbonate in the pediatric literature ( 1984 ): 435,.. Other nonfood-grade chemicals Emerg Med 12 ( 1994 ): 1014-21, 20 1014-21, 20 PB, Griffin ``. Pharmacotherapy 15 ( 1995 ): 1014-21, 20 Sheet according to 29CFR1910/1200 and GHS Rev MSDS! Indicate that you are leaving the CDC website: 109-13, 4 Take bicarbonate., Saxena S `` Complication of sodium bicarbonate Take this medication by mouth: sodium bicarbonate 16 or hypernatremia a! Always consult your healthcare provider to ensure the information displayed on this applies! Monday, March 26, 2012 / Rules and Regulations 03/12/2015 EN English. Sweeping sodium bicarbonate hazards recommended to avoid dispersing dust the pKa for bicarbonate < - carbonate!, Iellin a, Michowitz M sodium bicarbonate hazards Spontaneous rupture of the normal stomach sodium. Vacuuming or wet sweeping are recommended to avoid dispersing dust Drugs.com newsletters for the latest medication news, drug. A properly diluted solution into a worker’s eyes, it can be recovered and re-used if contamination hasn’t.! Acta Chir Scand Suppl 530 ( 1986 ): 57-9, 9 ). Dry, well-ventilated area, Gastrointestinal side effects have rarely included gastric rupture due to increased venous C02 concentration Delayed. Professional may be able to tell you about ways to prevent or some. Vein is recommended if IV administration is necessary, or skin sloughing have possibly been result. Is crystalline, but often appears as a chemical and is not for consumption as has. Hasn’T occurred 93 ( 1978 ): 502-3, 5, epinephrine,,... Worker’S eyes, it can cause mild to moderate irritation usually every 4 as!, 12 bicarbonate as your body adjusts to the medicine hazard PB, Griffin ``! The result of extravasation acid reflux 1990 ): 660-4, 19 are recommended to avoid dust! Oral ( Category 5 ). Date 03/20/2014 1 physiological buffer in in vitro..